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How Can 5-HT3 Receptor Antagonists Exert Analgesic Properties?
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نویسنده
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Norouzi Abbas ,Fakhfouri Gohar ,Rahimian Reza
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منبع
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acta medica iranica - 2012 - دوره : 50 - شماره : 4
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چکیده
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See ondansetron pretreatment reduces pain on injection of propofol by zahedi h, maleki a, rostami g on pages 239-243 (1). 5-ht3 receptors occur on various components of the pain modulation system. expressed on peripheral nerve endings and autonomic afferents as well as in the monoaminergic descending inhibitory system and certain brain regions, 5-ht3 receptors play an indispensable role in spinal pain transmission and endogenous pain suppression.
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آدرس
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tehran university of medical sciences tums, Brain and Spinal Cord Injury Repair Research Center, ایران, shahid beheshti university of medical sciences, School of Medicine, Department of Pharmacology, ایران, tehran university of medical sciences tums, School of Medicine, Brain and Spinal Injury Repair Research Center, Department of Pharmacology, ایران
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پست الکترونیکی
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rahimian78@gmail.com
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Authors
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