the impact of covid-19 pandemic on physical activity and health measures in patients with multiple sclerosis

The covid-19 pandemic restrictions may have significant implications for patients with multiple sclerosis (ms). the objective of this study is to explore the impact of the pandemic on physical activity levels and health outcomes among ms patients, as well as to examine potential associations between these factors. in this cross-sectional study, 197 patients with confirmed ms diagnosis were included. physical activity and health status were assessed using international physical activity questionnaire-long form (ipaq-lf) and short form 36 health survey questionnaire (sf-36) during the period of restrictions. the relationship between clinical characteristics, physical activity levels and health status parameters were examined. a total of 45 participants (22.8%) scored low, 73 (37.1%) scored moderate, and 79 (49.1%) achieved a high level of physical activity during the covid-19 pandemic. we observed no significant association between total physical activity and any domains of sf-36 health status, except for pain. however, correlations were found between ipaq and sf-36 domains. specifically, walking showed positive correlations with physical functioning, physical limitation, general health, and physical component summary score. vigorous activity demonstrated a negative correlation with social functioning, while moderate activity displayed a positive correlation with energy levels. despite the challenges of home isolation and quarantine, most of our participants managed to achieve a moderate to high level of physical activity, while their overall health status was found to be moderate. additionally, significant correlations were identified between the domains of health status and different types of physical activity, particularly walking. further studies are warranted to optimize the care and support provided to patients with ms.