assessment of infantile psychomotor development status in 6 and 12-month-old iugr infants: a historical cohort study

Intrauterine growth restriction (iugr) is responsible for different post-natal adverse outcomes. this study aimed to evaluate the post-natal psychomotor development status in 6 and 12-month-old iugr infants who received early preventive interventions. a historical cohort study was done at an iranian hospital (2019). the case group included one-year-old infants with a history of iugr at birth. this group was visited every 2 months to evaluate their growth and neurodevelopmental status. their parents had also received some training to improve their infant's sensory and motor skills. the control group comprised one-year-old healthy infants with a history of appropriate for gestational age (aga) at birth. data related to psychomotor developmental indices based on the asq questionnaire at 6 and 12-month for both groups was extracted from subjects' records. infants' psychomotor development status was compared between groups. forty-one infants with a history of iugr and 43 healthy control infants were included in this study. there were significant differences between 2 groups associated with abnormalities in all evaluated psychomotor skills, including gross motor (p=0.014), problem-solving ability (p=0.049), communication (p=0.031), fine motor (p=0.016) and personal-social (p=0.016) at 6 months. after one year of family-based interventions for the case group, significant differences between groups were notable in only fine motor (p=0.016) and personal-social skills (p=0.031). at 12 months, the psychomotor disorders related to gross motor, problem-solving ability, and communication were significantly alleviated in the iugr group. early preventive family-based interventions can improve the neurodevelopmental outcomes in 12-month-old iugr infants.