study of genome, vaccine and probable anti viral drugs to save the world from the capture of sars-cov-2: a mini-review

The coronavirus disease 2019 (covid-19) is a single-stranded rna (+) virus and causes infectious disease by the viral strain severe acute respiratory syndrome coronavirus 2 (sars-cov-2). now, covid-19 has become pandemic, and there are neither potential vaccines nor drugs discovered. its rna contains genes for structural (s, e, m, n) and non-structural proteins (plpro, 3clpro, rdrp, hel). interaction between the s protein of sars-cov-2 and the ace 2 receptor of the host cell plays a vital role in the entry of the virus into the cell. favipiravir, ribavirin, remdesivir, galidesivir, lopinavir, ritonavir, chloroquine, and hydroxychloroquine are the few effective drugs against sars-cov-2. live attenuated virus (mutant mers-cov and sars-cov or recombination with another live attenuated virus) can act as vaccine platforms against sars cov-2 along with dna vaccine and subunit vaccine