Acinar Cystic Transformation of the Pancreas: A Diagnostic Problem

Acinar cystic transformation (act) or acinar cell cystadenoma is a rare benign tumor of the pancreas. their clinical presentation is nonspecific, thus hampering their detection and frequently leading to misdiagnosis. in this report, we present a case of act of the pancreas in a 54-year-old man that was vague abdominal symptoms. a magnetic resonance imaging was shown a well-defined cystic mass located in the head of the pancreas, measuring 57×47×23 mm. our patient was treated by pancreaticoduodenectomy. in the macroscopic examination of the mass, a multicystic lesion was found in cream-colored pancreatic tissue. histological and immunohistochemical studies examination revealed a cystic mass containing multiple cysts at varying sizes, lined by epithelial cells without atypia and positive staining of ck7, ck8/18, and ck19. a high index of clinical suspicion is required to diagnose this tumor. the surgical approach is to ensure accurate diagnosis and to avoid complications.