Random Urine Protein Creatinine Ratio as a Preadmission Test in Hypertensive Pregnancies with Urinary Protein Creatinine Ratio

To evaluate the value of random urinary protein creatinine ratio in prediction of 24h proteinuria in hypertensive pregnancies. method: random urine samples and routine 24h urine collections were collected from hypertensive pregnant women (n=100). reliability of random urinary protein¡vcreatinine ratio was assessed by receiver operator characteristic (roc) curve to detect significant proteinuria („d300mg/day) using 24h. urine protein as a gold standard. forty six patients (46%) had significant proteinuria. the random protein creatinine ratio was correlated to 24h urine protein excretion (r2=0.777, p<0.001) area under roc curve to predict proteinuria was 0.926 (95% ci: 0.854¡v0.995, p<0.001). a cut off value of 0.22mg/mg for protein creatinine ratio best predicted significant proteinuria with sensitivity, specificity, positive and negative predictive values of 87%, 92.6%, 90.6% and 89.3% respectively. random urinary protein creatinine ratio is a simple inexpensive and excellent alternative to 24h urine collection. it's helpful in diagnosis of preeclampsia and can be used as a pre admission test in pih cases.