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   different breast cancer subtypes in women more than 65-year-old  
   
نویسنده sanaee pour arezoo ,pourali leila ,joudi mona ,taghizadeh ali ,salehi maryam ,gazanchian mehrdad ,nouri hosseini golshid
منبع acta medica iranica - 2018 - دوره : 56 - شماره : 11 - صفحه:698 -703
چکیده    Breast cancer is the most common malignancy of females. breast cancer is a heterogenic disease; it consists of several subtypes based on the expression of different genes. risk factors associated with each subtype is not completely understood, yet. moreover, recognizing the cancer subtypes may alter the treatment plan. the aim of this study was to evaluate different breast cancer subtypes in women more than 65-year-old. this was a cross-sectional study done on patients with breast cancer aged 65 years and older presenting to clinics of emam reza and omid hospitals, mashhad, iran between 2005 and 2015. statistical analysis was carried out using spss ver. 16. p<0.05 was considered statistically significant.a total of 225 breast cancer patients age 65 and older were included in our study. when we categorized our patients by breast cancer subtypes, 69.8% had the luminal a, b subtype, 23.1% had triple-negative subtype, and the remaining 7.1% had her-2 enriched subtype.different breast cancer subtypes in patients aged 65-year-old and higher were luminal a, b, her-2 enriched and triple-negative, respectively. we also showed that patients with luminal a, b subtypes had significantly higher bmi and bsa compared to other subtypes.
کلیدواژه breast cancer ,diagnosis ,age ,metastasis
آدرس mashhad university of medical sciences, school of medicine, ایران, mashhad university of medical sciences, school of medicine, department of obstetrics and gynecology, ایران, mashhad university of medical sciences, surgical oncology research center, ایران, mashhad university of medical sciences, surgical oncology research center, ایران, mashhad university of medical sciences, school of medicine, department of socio-medicine, ایران, mashhad university of medical sciences, school of medicine, student research committee, ایران, mashhad university of medical sciences, school of medicine, student research committee, ایران
 
     
   
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