Gastrointestinal Manifestations in A Child With Mastocytosis

Mastocytosis is characterized by the accumulation of mast cells in different tissues either in the skin or extracutaneous organs. herein, a 13-year-old girl is presented who suffered from intermittent abdominal pain, nausea, diarrhea with erythematous, and papulous cutaneous lesion. she had a history of same lesions from the age of four years. since 8 months ago, the patient presented with digestive complaints. the histopathological examination of the cutaneous lesions approved the diagnosis of mastocytosis. h1 and h2 antagonists were prescribed for her, while a mast cell stabilizer for digestive and cutaneous symptoms was also utilized, which improved the signs and symptoms of the patient.