Trends in antibiotic resistance of staphylococcus aureus from asymptomatic nasal carriers

Objective: to evaluate the trends of antibiotic resistance pattern of staphylococcus aureus (s. aureus) isolated from nares of healthy volunteers. methodology: participants belonging to,community associated (ca) and hospital associated (ha) environment were included in the study. a total of 207 nasal swab samples were processed for the isolation of s. aureus using conventional identification procedure. the antibiotic sensitivity testing for the isolates was done using kirbey-baur disk diffusion test. results: s. aureus was found in 27% of the samples. maximum resistance (60%) was observed against erythromycin antibiotic. statistically significant differences were seen in the percentages of s. aureus resistance against clindamycin,ciprofloxacin and methicillin between ha and ca. odds ratio (or) for clindamycin,ciprofloxacin and methicillin were calculated to be 5.91,3.84 and 11.9 while the p values were 0.015,0.040 and 0.001 respectively. conclusion: an association of clindamycin and ciprofloxacin resistance with cas. aureus and a statistically significant association of methicillin resistance with ha s. aureus were observed. © 2017,postgraduate medical institute. all rights reserved.