antibacterial activity of silver nanoparticles synthesized by hexane extract of some freshwater algae against multi-drug resistance bacteria

Objectives antibiotic-resistant bacteria have become a worldwide concern due to the unintentional use of antibiotics, which has resulted in bacterial strains resistant to many or all available antibiotics. the primary and secondary metabolites found in algae play a major role in the conversion of silver nitrate to silver nanoparticles (agnps). materials and methods hexane extract of some freshwater algae was used in the process of making these nanoparticles. the reaction solution’s color changing from yellow to dark brown due to the surface plasmon resonance’s excitation serves as evidence for this. agnps were identified using uv-vis spectroscopy, proteins and phenols were found to play a significant role in the formation of agnps, according to research done using fourier transformation-infrared (ftir) to identify the effective algae group that contributes to the formation of those nanoparticles. a scanning electron microscope (sem) was used to characterize the shapes and sizes of the synthesized agnps, which included spherical, rod-like, and hexagonal structures. vitek compact 2 system-diagnosed multi-drug resistant (mdr) bacteria were used to test agnps’ antibacterial activity. results a study was conducted on the antibacterial effectiveness of biosynthetic silver nanoparticles against selected isolates of mdr bacteria. the results showed that silver nanoparticles prepared from hexane extract of the isolated algae at a concentration of 100% showed greater inhibition than crude extract of all types of pathogenic bacteria, with statistically significant differences (p<0.05). conclusions the silver nanoparticles prepared from hexane extract was more effective against g-ve and g+ve mdr bacterial isolates (e. coli, p. aeruginosa, s. aureus, k. pneumoniae, and e. faecalis) at concentrations 100 μg/ml than those prepared without silver nanoparticles hexane extract, the extract from cladophora neglecta silver nanoparticles demonstrated highly significant inhibition in all species of bacteria.

antibacterial activity of silver nanoparticles synthesized by hexane extract of some freshwater algae against multi-drug resistance bacteria

objectivesantibiotic-resistant bacteria have become a worldwide concern due to the unintentional use of antibiotics, which has resulted in bacterial strains resistant to many or all available antibiotics. the primary and secondary metabolites found in algae play a major role in the conversion of silver nitrate to silver nanoparticles (agnps). materials and methodshexane extract of some freshwater algae was used in the process of making these nanoparticles. the reaction solution’s color changing from yellow to dark brown due to the surface plasmon resonance’s excitation serves as evidence for this. agnps were identified using uv-vis spectroscopy, proteins and phenols were found to play a significant role in the formation of agnps, according to research done using fourier transformation-infrared (ftir) to identify the effective algae group that contributes to the formation of those nanoparticles. a scanning electron microscope (sem) was used to characterize the shapes and sizes of the synthesized agnps, which included spherical, rod-like, and hexagonal structures. vitek compact 2 system-diagnosed multi-drug resistant (mdr) bacteria were used to test agnps’ antibacterial activity.   resultsa study was conducted on the antibacterial effectiveness of biosynthetic silver nanoparticles against selected isolates of mdr bacteria. the results showed that silver nanoparticles prepared from hexane extract of the isolated algae at a concentration of 100% showed greater inhibition than crude extract of all types of pathogenic bacteria, with statistically significant differences (p<0.05). conclusionsthe silver nanoparticles prepared from hexane extract was more effective against g-ve and g+ve mdr bacterial isolates (e. coli, p. aeruginosa, s. aureus, k. pneumoniae, and e. faecalis) at concentrations 100 μg/ml than those prepared without silver nanoparticles hexane extract, the extract from cladophora neglecta silver nanoparticles demonstrated highly significant inhibition in all species of bacteria.