Interstitial pregnancy treated with a single-dose of systemic methotrexate: A successful management

Interstitial pregnancy is an ectopic pregnancy at high hemorrhagic risk. it often poses a diagnostic and therapeutic challenge to the clinician,with a significant risk of morbidity and mortality. it presents a difficult management problem with no absolute standard of care; the most appropriate treatment technique for these pregnancies remains controversial. we describe a case of unruptured interstitial pregnancy successfully treated with a single-dose of systemic methotrexate with subsequent ultrasound and serum beta human chorionic gonadotropin monitoring. medical management can be a safe and successful option in selected cases that satisfy specific criteria and in women who are able to be monitored after treatment. © 2015,isfahan university of medical sciences(iums). all rights reserved.