Psychometric properties and validation of Persian version of quality of life in epilepsy inventory (QOLIE-89)

Background: several epilepsy-specific quality of life questionnaires have been developed. one of them is quality of life in epilepsy-89 version. the objective of this study was to develop a persian version of qole-89 and confirm its psychometric properties. materials and methods: participants were 75 patients with epilepsy. the quality of life questionnaire was adapted to persian language through a translation and translation-back procedure. internal consistency by cronbach’s α, was determined and construct validity was assessed by correlation with ghq-12 and bdi-pc and discriminant validity was confirmed by comparing scores for known groups. results: reliability based on internal consistency (cronbach›s α) for qoie-89 was 0/96 and for 17 subscales was varied form 0/70 to 0/89 and test-retest reliability (pearson’s correlation coefficient) for the farsi version of the qolie-89 ranged from 0.75 to 0.88. total score of qolie-89 discriminated well between the patients according to depression severity and drug resistance and seizure controllability. correlation between the total scores, bdi-pc and ghq-r to confirm construct validity was 0/55 and 0/63, respectively. conclusion: in this cross-sectional survey, persian version of the qolie-89 was reliable and showed properties supporting the construct and discriminant validity at a level comparable with the original and some other versions. thus, this questionnaire has suitable properties in iranian population and can be used in clinical trials with epileptic patients.