Letter to Editor

I appreciate dr. khazaei’s interest in our article “aqueous concentrations of vegf and soluble vegf receptor-1 (svegfr1) in diabetic retinopathy patients” and have read with interest the comments sent by him. we found no significant difference in the aqueous fluid levels of vascular endothelial growth factor (vegf) in nonproliferative diabetic retinopathy (npdr) patients compared with nondiabetic patients, whereas that of svegfr-1 was significantly decreased in npdr patients compared with nondiabetic patients. there was no significant different vegf/svegfr-1 ratio between groups in our study (0.39 ± 0.04 in controls vs 0.29 ± 0.04 in npdr patients, p = 0.3).