Effects of whole‑body vibration training on fibrinolytic and coagulative factors in healthy young men

Background: the aim was to evaluate effects of 5‑week whole body vibration (wbv) training with different amplitudes and progressive frequencies on fibrinolytic/coagulative factors. materials and methods: 25 subjects were divided randomly in high or low‑amplitude vibration, and control groups. training consisted of 5‑week wbv with amplitudes 4 or 2 mm. plasma samples were analyzed before and after training. statistical analysis was done using one‑way analysis of variance and wilcoxon signed ranked test. p <0.05 was considered significant. results: high‑amplitude vibration caused an increase in tissue plasminogen activator (tpa) (p = 0.028) (pretest: 1744.61 ± 707.95; posttest: 2313.63 ± 997.19 pg/ml), and decrease in plasminogen activator inhibitor‑1 (pai‑1) (p = 0.033) (pretest: 97.94 ± 34.37; posttest: 85.12 ± 36.92 ng/ml). fibrinogen and plasminogen were not changed significantly. low‑amplitude vibration caused an increase in tpa (p = 0.006) (pretest: 2208.18 ± 1280.37; posttest: 3492.72 ± 3549.22 pg/ml). pai‑1, fibrinogen and plasminogen were not changed significantly. there were no significant differences between groups. conclusion: amplitude of vibrations in wbv training may affect fibrinolytic factors.