Preparation and pharmaceutical evaluation of nicotinamide stick for eradication of Staphylococcus epidermidis

Background: staphylococcus epidermidis is a part of the skin's normal flora that can cause acne. this study was designed to evaluate the efficacy of nicotinamide as a stick in eradication of staphylococcus. materials and methods: for evaluating of anti-microbial effect on s. epidermidis used well plate method. we chose five plates for nicotinamide and five for mupirocin. the zones of inhibition were measured and compared. results: the results showed nicotinamide stick had anti-microbial effects, but in comparison to mupirocin it was significantly less (p = 0.003). conclusion: nicotinamide stick was made and evaluated. this study showed that nicotinamide had anti-microbial effect on staphylococcus.