The effects of vitamin E and selenium on cisplatin‑induced nephrotoxicity in cancer patients treated with cisplatin‑based chemotherapy: A randomized, placebo‑controlled study

We read with great interest the article by hemati and colleagues, entitled “the effects of vitamin e and selenium on cisplatin‑induced nephrotoxicity (cin) in cancer patients treated with cisplatin (cp)‑based chemotherapy: a randomized, placebo‑controlled study,” published recently in your esteemed journal. they studied 22 patients, who received 400 iu vitamin e and 200 μg selenium daily and 24 patients received placebo. they found significant differences in glomerular filtration rate between the two groups after the third cycle and 1 month after the end of chemotherapy. they concluded that vitamin e and selenium can be used to reduce cin. we congratulate the authors for their findings and their effort to find a way to reduce cin.