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Risk factors of the efficacy of hepatitis B vaccine in health‑care workers
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نویسنده
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salehi hassan ,salehi marzieh ,kalbasi nader ,salehi maryam ,sharifian jalil ,salehi mohammad mahdi
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منبع
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journal of research in medical sciences - 2020 - دوره : 25 - شماره : 2 - صفحه:1 -3
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چکیده
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Background: conventional hepatitis b virus vaccination fails to achieve efficient protection in about 5%–10% of the world population. different factors influence the immunogenicity of hepatitis b vaccine. this study aimed to evaluate these factors in health‑care workers. materials and methods: this was a descriptive study which was implemented among 140 of medical and dental staff working as health‑care workers who were low responder after vaccination entered the study. results: age (>40 years), weight (body mass index >25), immunodeficiency diseases, (primary immune deficiency and immunosuppressant drugs), diabetes mellitus, and smoking were the important factors. conclusion: in the high‑risk group of hepatitis b disease, the risk factors of immunogenicity must be evaluated at vaccination and check titers of antibody after vaccination.
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کلیدواژه
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Health‑care workers ,hepatitis B ,vaccine efficacy
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آدرس
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isfahan university of medical sciences, infectious diseases and tropical medicine research center, Iran, isfahan university of medical sciences, medical school, department of infectious diseases, Iran, khoraskan university, dentistry faculty, department of oral and facial pathology, Iran, isfahan university of medical sciences, dentistry school, dentistry student research center, Iran, shahid beheshti university of medical sciences, dentistry school, oral surgery department, Iran, isfahan university of medical sciences, dentistry school, dentistry student research center, Iran
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Authors
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