Association of hypoproteinemia in preeclampsia with maternal and perinatal outcomes: A retrospective analysis of high-risk women

The aim of this study was to evaluate maternal and perinatal outcomes in preeclampsia (pe),according to the value of albumin. materials and methods: preeclamptic women were retrospectively divided into mild hypoproteinemia (mhp,n = 220) and severe hypoproteinemia (shp,n = 79) pe according to the value of albumin. the maternal and perinatal outcomes were evaluated in both groups. results: two hundred and ninety-nine single pregnancies complicated by pe were included in this study. gestational age at delivery was earlier in shp than mhp (p < 0.01). severe hypertension,abnormal liver function,abnormal renal function,ascites,and abruption occurred more frequently in shp than in mhp (p < 0.01,0.03,<0.01,0.01,and 0.04,respectively). women in shp had a higher rate of cesarean section than those in mhp (p = 0.04). fetal growth restriction infants were more frequent in shp than in mhp (p < 0.01). the occupancy rate of the neonatal intensive care unit was higher in shp than in mhp (p < 0.01). conclusion: shp pe is associated with a higher risk of adverse pregnancy outcome than mhp pe,deserving closer surveillance during pregnancy. � 2016 journal of research in medical sciences.