Cognitive rehabilitation in patients with nonamnestic mild cognitive impairment

The nonamnesic type of mild cognitive impairment (na-mci) is predementia state with subtle decline incognitive domains except memory. although cognitive rehabilitation (cr) has been investigated in amnesic type of mci,we could not find any trial that rehabilitated na-mci exclusively. we studied the effectiveness of cr on na-mci. materials and methods: this study was a blinded,randomized clinical trial. individuals with age of 60 years or more,complete self-directedness and diagnosis of na-mci,based on neuropsychiatry unit cognitive assessment tool,were selected. the 51 patients were randomly assigned into three groups: cr,lifestyle (ls) modification,and the control group (cg). neuropsychological tests for executive functioning were assessed at the baseline,after the interventions,and 6 months later. results: the mean score of the “design fluency” test increased significantly in cr,compared to ls and cg (p = 0.007). in “five-point” test,mean score increased significantly in cr (p = 0.03). there was higher mean score of behavioral rating inventory of executive function for adults in cr (p = 0.01). conclusion: consideration of the mci subtypes allows us to target specific cognitive domains,such as information processing,for better cr outcome. cr may result in better performance of executive functioning of daily living. � 2016 journal of research in medical sciences.