Prognostication of Sino-Nasal Mucormycosis

Introduction: for the purpose of prognostication of sinonasal mucormycosis, a detailed analysis of the clinical, diagnostic, therapeutic and outcome parameters has been contemplated. materials and methods: retrospectively data was collected for all patients of sinonasal mucormycosis managed in a tertiary care hospital in last 5years. results: diabetes was the commonest comorbidity among total of 52 cases. disease extent-wise, 16, 23 and 13 patients had sino-nasal (sn), rhino-orbital (ro) and rhino-orbito-cerebral (roc) mucormycosis respectively. median cumulative amphotericin-b administered was 3.5gms and 94.2% of cases underwent surgical debridement depending on the disease extent. with a median follow-up of 18months, 67% of the patients are alive and disease free, 2% are under treatment and 29% of patients have expired. the mortality rate was 12.5% in sn, 30.5% in ro and 38.5% in roc mucormycosis. palatal and orbital involvement is associated with statistically significant mortality risk at one month. conclusions: mortality rate in sino-nasal mucormycosis can be significantly curtailed with prompt control of underlying comorbidity, aggressive medical and adequate surgical management.