chondroradionecrosis of the larynx in a patient with laryngeal: a case report

Introduction: actinomycosis of the larynx has been rarely reported in the literature and usually occurs in patients with a history of laryngeal carcinoma and radiation therapy. however, its co-existence with chondroradionecrosis due to radiotherapy is even rarer. the most common site of infection is the cervicofacial region, especially in the submandibular area.   case report: here we report a 63-year-old male with a history of chemoradiotherapy because of laryngeal cancer 1 year earlier who presented with laryngeal actinomycosis. after prolonged penicillin-based treatment, the patient underwent thyroid cartilage defect reconstructive surgery because of a laryngocutaneous fistula due to chondroradionecrosis. the diagnosis, work-up, and management of the case are discussed, as well as a review of the literature.   conclusion: although actinomycotic infection of the larynx is rare, it should be considered in the differential diagnosis of laryngeal complaints, especially in immunocompromised patients.