intratympanic injection of dexamethasone and electrocochleographic data in cases of definite one sided refractory meniere’s disease

Introduction: meniere’s disease (md) is a disease of the inner ear that presents itself with repeated episodes of vertigo (96.2%), tinnitus (91.1%), and sensorineural hearing loss (87.7 %). in this article we sought to assess the effects of intratympanic (it) injections of dexamethasone on definite cases of md using electrocochleography (ecog). materials and methods: in this hospital-based case series in 36 patients, we measured audiometric values and ecog in all patients before, 1 month and 6 months after 4-mg/ml it injections of dexamethasone. results: four patients (11%) had improved hearing following the intervention. no difference in pure tone audiometry (pta) was observed following it injections (p=0.492), while speech discrimination score (sds) was significantly improved (p=0.008). there was a significant improvement in vertigo 1 month after it injections (p<0.001), although this effect did not last for 6 months. no significant change in ecog was observed between before and after treatment (p=0.052). conclusion: it dexamethasone injections can improve vertigo in definite cases of md, although it seems that the effect is only temporary.