Isolated Laryngeal Amyloidosis

Introduction: amyloidosis comprises a heterogeneous group of disorders characterized by the deposition of amyloid protein in various organs of the body. the larynx is one of the rarer sites where amyloidosis occurs. case report: a 36-year-old man presented with a two-year history of hoarseness of voice. he had a positive history of smoking, but no history of long-term consumption of alcohol. physical examination revealed a pinkish mass about 1.5 × 1.5 cm in size on his left false vocal cord (fvc) extending to the left arytenoid, which resulted in asymmetry of the posterior larynx. he also had a chronic perforation of the right tympanic membrane with a conductive hearing loss consisting of a 50 db gap in pure tune audiometry. the fvc mass was excised with a co2 laser and on follow-up his voice got much better, but the hoarseness was not fully resolved. conclusion: amyloidosis of the larynx is a rare, usually benign process but the area is the most common site for isolated amyloid deposits to occur in the head and neck.