histopathological investigation of sarcoptes scabiei infestation in sheep population in diyala province, iraq

Background: mange, primarily caused by the parasitic mite sarcoptes scabiei, poses a serious health threat to many mammalian species, including domesticated and wild animals.objectives: this study investigates the major effects of s. scabiei, the causative agent of scabies, focusing on the sheep population in diyala province, iraq. the disease results in severe clinical symptoms, such as intense itching, hair loss, and secondary infections, and may negatively impact the productivity and wool quality of affected sheep. despite its importance, the histopathological alterations induced by s. scabiei in sheep have remained poorly documented.methods: to explore these alterations, skin samples were collected from sheep diagnosed with scabies in diyala province. the tissue samples were stained using hematoxylin and eosin (h&e) and examined under a light microscope to identify and document pathological changes caused by the mite.results: histopathological analysis revealed significant abnormalities, including hyperkeratosis, acanthosis, neutrophilic infiltration, and hemorrhage. s. scabiei in the stratum corneum, accompanied by follicular hyperkeratosis and acute cellular swelling, highlights the intense inflammation and tissue damage resulting from the infestation.conclusion: this study confirms distinct histopathological changes in sheep’s skin affected by sarcoptic mange.