Antiparasitic efficacy of worm wood (Artemisia absinthium) alcoholic extract on syphacia obvolata

Backgrounds: occurrence of resistance against antiparasitic drugs has made it essential for researchers to find new sources for antiparasitic drugs. objectives: this study was performed to determine the efficiency of alcoholic extract of worm wood (artemisia absinthium) on syphasia parasite. methods: artemisia absinthium extract was examined on 3 groups of mice at 2.5%, 5% and 10% concentrations. a group of positive control received pyrantel pamoate, while negative control group was treated by a solution containing no extract. mice were treated orally 28 days after infection by syphacia eggs. the efficacy of treatment was determined by syphacia eggs in the feces. results: in groups that received either 5% or 10% concentrations of a. absinthium extract or pyrantel pamoate, microscopic examinations of the feces demonstrated no syphacia eggs. conclusions: data obtained from the present study showed that the alcoholic extract of artemisia absinthium may lead to a decline in the number of syphacia eggs in the feces with minimal side effects. the extract of this plant can probably be used as a suitable alternative in the treatment of some parasitic diseases