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   Lineage Switch in Childhood Leukemia: A Case Report and Review of Literature  
   
نویسنده nazari shiva ,malek fatemeh ,zavvar navid
منبع iranian journal of blood and cancer - 2016 - دوره : 8 - شماره : 3 - صفحه:86 -87
چکیده    Acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. the conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. it has been rarely reported in the literature. in leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. herein, we report a 7-year-old child with acute lymphoblastic leukemia which switched to acute myeloid leukemia upon relapse.
کلیدواژه Leukemia ,Children ,Cell lineage
آدرس shahid beheshti university of medical sciences, pediatric congenital hematologic disorders research center, mofid children’s hospital, ایران, shahid beheshti university of medical sciences, pediatric respiratory diseases research center, national research institute of tuberculosis and lung diseases (nritld), ایران, shahid beheshti university of medical sciences, pediatric congenital hematologic disorders research center, mofid children’s hospital, ایران
 
     
   
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