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Rosai-Dorfman Disease: A Case Report and Literature Review
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نویسنده
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Shamsian BS ,Arabi N ,Kazemi Aghdam ,Rouzrokh M ,Ghojehvand N ,Azma R ,Kaji Yazdi M ,Alavi S ,Arzanian MT
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منبع
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iranian journal of blood and cancer - 2014 - دوره : 6 - شماره : 3 - صفحه:155 -158
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چکیده
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Rosai-dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms whose etiology remains poorly elucidated. the diagnosis is based on immunohistochemistry. its treatment is poorly defined but the prognosis is usually favorable. here we report a 14 year old boy who presented with massive bilateral cervical lymphadenopathy. histopathological examination demonstrated lymphophagocytosis (emperipolesis) consistent with a diagnosis of rosai-dorfman disease. the clinical and histological aspects of the disease are discussed as a rare cause of lymphadenopathy.
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کلیدواژه
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Rosai-Dorfman disease ,emperipolesis ,case ,Iran
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آدرس
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shahid beheshti university of medical sciences, Mofid children’s hospital, Pediatric Congenital Hematological Disorders Research Center, ایران, shahid beheshti university of medical sciences, Mofid children’s hospital, Pediatric Congenital Hematological Disorders Research Center, ایران, shahid beheshti university of medical sciences, Mofid children’s hospital, Department of pediatric pathology, ایران, shahid beheshti university of medical sciences, Mofid children’s hospital, Department of pediatric surgery, ایران, shahid beheshti university of medical sciences, Mofid children’s hospital, Department of pediatric radiology, ایران, shahid beheshti university of medical sciences, Mofid children’s hospital, Department of pediatric radiology, ایران, shahid beheshti university of medical sciences, Mofid children’s hospital, Pediatric Congenital Hematologic Disorders Research Center, ایران, shahid beheshti university of medical sciences, Mofid Children Hospital, Pediatric Congenital Hematological Disorders Research Center, ایران, shahid beheshti university of medical sciences, Mofid children’s hospital, Pediatric Congenital Hematologic Disorders Research Center, ایران
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Authors
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Kazemi Aghdam
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