Methaemoglobin Content and NADHMethaemoglobin Reductase Activity of Three Human Erythrocyte Genotypes

Background: to study methaemoglobin content and nadh-methaemoglobin reductase activity of three human erythrocyte genotypes (hbaa, hbas and hbss).materials and methods: studies to ascertain methaemoglobin concentration and level of nadh-methaemoglobin reductase activity of three human erythrocyte genotypes (hbaa, hbas and hbss) were carried out in forty-three (43) healthy male participants of confirmed erythrocyte genotypes: hbaa (n=15), hbas (n=15) and hbss (n=13).spectrophotometric method was used for determination of the two erythrocyte parameters.results: whereas methaemoglobin concentrations in the three erythrocyte genotypes was in the order: hbas0.05) in methaemoglobin concentration and nadh-methaemoglobin reductase activity between hbaa and hbas erythrocytes.conclusion: the results showed a relationship between erythrocyte nadh-methaemoglobin reductase activity and methaemoglobin concentration.