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Mathematical Modeling and Lyapunov-Based Administration in Cancer Chemotherapy
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نویسنده
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Ghaffari A. ,Nasserifar N.
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منبع
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iranian journal of electrical and electronic engineering - 2009 - دوره : 5 - شماره : 3 - صفحه:151 -158
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چکیده
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In this paper a new mathematical model is developed for the dynamics between tumor cells, normal cells, immune cells, chemotherapy drug concentration and drug toxicity. then, the theorem of lyapunov stability is applied to design treatment strategies for drug protocols that ensure a desired rate of tumor cell kill and push the system to the area with smaller tumor cells. using of this theorem a condition for drug administration to patients so that solution of the system of equations always tends to tumor free equilibrium point is proposed.
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کلیدواژه
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Lyapunov stability ,cancer ,chemotherapy
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آدرس
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k.n.toosi university of technology, Department of Mechanical Engineering, ایران, k.n.toosi university of technology, Department of Mechanical Engineering, ایران
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پست الکترونیکی
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naser.naserifar@gmai1.com
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Authors
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