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Coated gellan gum hydrogel as a drug carrier for colon targeted drug delivery
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نویسنده
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norazemi n.f. ,rose l.c. ,amin k.a.m. ,suhaimi h. ,yee c.s.
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منبع
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journal of sustainability science and management - 2017 - دوره : 2017 - شماره : Special Issue 2 - صفحه:36 -41
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چکیده
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Oral drug delivery system provides a simple mechanism and more convenient approach towards colon cancer treatment. yet,oral drug administration also faced some limitation passing through in the gastrointestinal tract before reaching the targeted area. in this work,a coated gellan gum hydrogel was proposed to increase the treatment efficiency in colon cancer treatment through oral administration using dip coating process. two types of coating materials,hydrocarbon (eicosane and docosane) and fatty acid (c12 and c16) were used. single and mixed coating materials were tested using dsc and the results obtained showed that the best coating material was hydrocarbon with a weight ratio of 40:60 of eicosane and docosane (e:d). © 2017 penerbit umt.
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کلیدواژه
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Coating materials; Colon cancer; Gastrointestinal tract; Oral administration; Polymer
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آدرس
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school of fundamental science,universiti malaysia terengganu,kuala nerus,terengganu, Malaysia, school of fundamental science,universiti malaysia terengganu,kuala nerus,terengganu, Malaysia, school of fundamental science,universiti malaysia terengganu,kuala nerus,terengganu, Malaysia, school of fundamental science,universiti malaysia terengganu,kuala nerus,terengganu, Malaysia, school of pharmaceutical sciences,universiti sains malaysia,pulau pinang, Malaysia
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Authors
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