|
|
|
|
NaHSO4-SiO2: An Efficient Reusable Green Catalyst for Selective C-3 Propargylation of Indoles with Tertiary Propargylic Alcohols
|
|
|
|
|
|
|
|
نویسنده
|
- - ,- - ,- -
|
|
منبع
|
iranian journal of chemistry and chemical engineering - 2015 - دوره : 34 - شماره : 3 - صفحه:11 -17
|
|
چکیده
|
Although several methods for the preparation of 4o propargyl indole derivatives have been published, this synthetic transformation is complicated by the tendency of 3o propargyl alcohols to form allenium intermediates in acidic media. it is therefore a challenge to find an efficient method for the c-3 propargylation of indoles with 3° propargylic alcohols. in this paper we wish to report on the successful application of silica gel impregnated with nahso4 as catalyst for the preparation of 4o propargyl indole derivatives.
|
|
کلیدواژه
|
Alkylation ,Catalyst ,Indole ,Propargylic alcohols ,Sodium bisulfate-silica
|
|
آدرس
|
Department of Chemistry, University of the, Department of Chemistry, University of the Free State, P O Box 339, Bloemfontein 9300, SOUTH AFRICA, South Africa, Department of Chemistry, University of the, Department of Chemistry, University of the Free State, P O Box 339, Bloemfontein 9300, SOUTH AFRICA, South Africa, Department of Chemistry, University of the, Department of Chemistry, University of the Free State, P O Box 339, Bloemfontein 9300, SOUTH AFRICA, South Africa
|
|
پست الکترونیکی
|
benzuidbc@ufs.ac.za
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|