Volumetric and Viscometric Studies of Nucleosides, Nucleotides and Furanose Sugar in Aqueous Medium from 288.15 to 298.15K

Density (p/g cm'3) and viscosity (r[/10'2gcm'ls~l=lcentipoise,cp) of guanosine monophosphate (gmp) and adenosine triphosphate (atp) referred to as nucleotide, and 2-deoxy adenosine (doa) and thymidine (tmd) as nueleoside along with their integral furanose sugar, 2-deoxy ribose (dor) from 0.0004 to 0.0014mol kg'1 solution have been measured at 288.15, 293.15 and 298.15k at atmospheric pressure. the p was fitted into the masson andr in jones-dole equations for apparent molal volume (v^/cm3mol'j) and viscosity coefficient ((rr-l)/m=b/kg mol'1=103gmol~1) data. the v§ and r were also regressed for v°§ and r|° values known as the limiting constants and illustrate solute-solvent and solute-solute interactions of systems. the apparent molal volume of their various integral units like adenine, guanine and thymine of nucleotides and nucleosides are estimated by v°§ the v°§ r|° andb values have been used to elucidate the hydrophilic and hydrophobic interactions. the v( values are negative over the whole range of the compositions which infer greater intermolecular forces and the biomolecules as water structure breakers.