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Separation of Sedative - Hypnotic Drugs with Mixed Micellar Liquid Chromatography
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نویسنده
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Hadjmohammadi Mohammad Reza ,ShariphiAghili Azadeh
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منبع
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iranian journal of chemistry and chemical engineering - 2005 - دوره : 24 - شماره : 2 - صفحه:59 -63
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چکیده
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Separation often sedative- hypnotic drugs was performed by rp-hplc using mixed micellar mobile phase. effect of temperature, type and amount of organic modifier in mobile phase on efficiency (n) and asymmetry factor (b/a) showed that, the appropriate conditions for a good separation were 35°c and 7% (v/v) butanol in mobile phase. variations of selectivity factor versus butanol concentration, mixture ofsds/brij- 35 concentrations andph of mobile phase showed that the appropriate conditions were 7%(v/v), 15 mm sds +1.0mm brij-35 and ph=3 in mobile phase respectively.
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کلیدواژه
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Sedative-hypnotic drugs ,High performance liquid chromatography ,Micellar liquid chromatography ,Mixed micellar liquid chromatography ,Separation of sedative-hypnotic drugs.
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آدرس
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university of mazandaran, ایران, university of mazandaran, ایران
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پست الکترونیکی
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hadjmr@ umz.ac.ir
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Authors
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