synthesis of magnetic novel hybrid nanocomposite (fe3o4@sio2/activated carbon( by a green method and evaluation of its antibacterial potential

Inorganic antibacterial nanoagents have more advantages compared to popularly organic agents due to chemical stability, thermal resistance, immunity, and long-term activity. in this study, a magnetically hybrid nanocomposite was prepared from the nigella sativa oil waste as an organic matrix in a green approach. the homogeneous distribution of core-shell fe3o4@sio2 nanoparticles on the activated carbon surface was carried out with a simple chemical method. characterization of the synthesized nanocomposite was performed by different analysis techniques such as scanning electron microscopy–energy dispersive spectroscopy, scanning electron microscopy, x-ray diffraction, and brunauer-emmett-teller surface area analysis. the antibacterial activities of the prepared nanoparticles against gram-positive and gram-negative bacteria were investigated and the minimum inhibitory concentration and the minimum bactericidal concentration values were compared to imipenem as a standard antibiotic. the effects of temperature, time, and the ratio of the activated carbon to fe3o4@sio2 on the mic and mbc values of the prepared nanocomposites were investigated. the obtained results reveal the substantial role of all of these parameters in the gram-positive antibacterial potential, especially for s. agalactiae bacteria. the results show that the new proposed nanocomposite could be an alternative for an effective filter against gram-positive bacteria alongside having magnetic properties.