molecular dynamics, biological study and extractive spectrophotometric determination of vanadium (v) - 2-methyl-8-quinolinol complex

An extractive spectrophotometric method is developed for the trace determination of vanadium (v). 2-methyl-8-quinolinol(mq) reacts with vanadium(v) to form a 1:2 (v : mq) light brown complex in an aqueous medium at 0.05 m ch3cooh concentration which is quantitatively extractable into chloroform exhibiting maximum absorbance in the range 397- 405 nm..the complex is synthesized in 1:2 ratio and the structure of the formed complex is elucidated on the basis of ir, nmr, and tga techniques aided with computational studies. the formed v (v)-mq complex is also screened for its in vitro antimicrobial activity. the method obeys beer’s law up to 6.2 μg v/ml with molar absorptivity and sandell’s sensitivity of 2.449 × 103 l/mol.cm and 0.0208 μg v/cm2, respectively, at 400 nm. the method is simple, rapid, and has good reproducibility with a standard deviation of ± 0.0027 absorbance units.