synthesis and characterization of γ-fe2o3@hap@β-cd core-shell nanoparticles as a novel magnetic nanoreactor and its application in the one-pot preparation of β-azido alcohols, β-nitro alcohols, and β-cyanohydrins

In this study, β-cyclodextrin(β-cd) supported, hydroxyapatite encapsulated γ-fe2o3 (γ-fe2o3@hap@β-cd) was successfully prepared and evaluated as a solid–liquid phase transfer catalyst and also a molecular host system and nanoreactor for the nucleophilic ring opening of epoxides in water for the preparation of β-azido alcohols, β-nitro alcohols, and β-cyanohydrins. the catalyst was characterized with ft-ir, xrd, tga and sem. this procedure offers several advantages including excellent regioselectivity, high yields, short reaction times, recyclable catalyst, easy separation of the catalyst through external magnet, and easy work-up