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An Efficient Protocol for the Synthesis of Carboacyclic Nucleosides via Aza-Conjugate Addition Reaction
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نویسنده
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Zolfigol Mohammad Ali ,Khazaei Ardeshir ,Moosavi-Zare Ahmad Reza ,Zare Abdolkarim ,Hasanijejad Ali Reza
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منبع
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iranian journal of chemistry and chemical engineering - 2010 - دوره : 29 - شماره : 4 - صفحه:67 -73
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چکیده
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A new efficient method for the synthesis of carboacyclic nucleosides as biologically interesting compounds via aza-conjugate addition of pyrimidine nucleobases to a,-unsaturated esters in the presence of catalytic amount of lioh.h2o (1.2-4.8 mol%) under microwave irradiation is described. this method affords the title compounds in good to excellent yields and in short reaction times.
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کلیدواژه
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Carboacyclic nucleoside ,Aza-conjugate addition reaction ,Pyrimidine nucleobase ,b-unsaturated ester ,Microwave
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آدرس
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bu ali sina university of hamadan, College of Science, Department of Chemistry, ایران, bu ali sina university of hamadan, Faculty of Chemistry, ایران, bu ali sina university of hamadan, Faculty of Chemistry, ایران, payame noor university, Department of Chemistry, ایران, persian gulf university, Faculty of Sciences, Department of Chemistry, ایران
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پست الکترونیکی
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khazaei_1326@yahoo.com
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Authors
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