One Pot Synthesis of Polyhydroquinolines Catalyzed by Sulfonic Acid Functionalized SBA-15 as a New Nanoporous Acid Catalyst under Solvent Free Conditions

Sulfonic acid functionalized sba-15 (sba-pr-so3h) as a new nanoporous acidcatalyst was used in the one-pot synthesis of polyhydroquinolines derivatives via the hantzsch fourcomponent condensation reaction of aldehydes, β - ketoesters, dimedone and ammonium acetateunder solvent free conditions with short reaction time in excellent yields. sba-pr-so3h was provedto be an efficient heterogeneous nanoporous solid acid catalyst (pore size 6 nm), which could beeasily handled and removed from the reaction mixture by simple filtration, and also recovered andreused without loss of reactivity.