The effect of two different intense training protocols on oxidative stress of liver tissue during puberty in male rats

Background: intense physical activity increases the production of reactive oxygen species in vital tissues such as the liver and causes oxidative stress.aim: this study investigates the effect of high-intensity interval training and intense endurance training on oxidative stress of liver tissue in immature male rats during puberty.materials and methods: a total of 24 male wistar rats (aged= 22 days, weight= 60±0.63 g), after one week of acclimatization, were divided randomly into three groups: control, iet, and hiit. rats were subjected to a four-week training on an animal treadmill. the effects of training treatment in rat liver were investigated by assaying oxidative stress biomarkers.results: comparing to control group, in both training groups significantly lower malondialdehyde (mda) was seen ((p(iet)= 0.016/ p(hiit)= 0.020). however, there were no statistical differences in glutathione peroxidase (gpx) (p= 0.463) and total antioxidant capacity (tac) activity levels (p= 0.194) among groups. hiit training significantly increased superoxide dismutase (sod) (p= 0.040) and catalase enzyme (cat) levels (p= 0.007). iet and hiit had significantly increased endurance performance (both: p= 0.001).conclusion: both training intensities did not lead to an increase in oxidative stress and can be used during puberty.