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evaluation of chemerin in diabetic type 2 patients with metabolic syndrome in both gender
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نویسنده
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hywar f.a. ,al-husaini f.k. ,falih i.q. ,elias n.g.
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منبع
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iranian journal of war and public health - 2022 - دوره : 14 - شماره : 4 - صفحه:409 -414
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چکیده
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Aims: chemerin abnormal level represents a risk indicator of visceral fat increase. it has a role in the incidence of inflammation, insulin resistance, metabolic syndrome, obesity, and diabetes. this study aimed to evaluate chemerin level in diabetic type 2 patients with metabolic syndrome in both genders. materials & methods: this study was carried out on the patients referred to the al-yarmouk teaching hospital in 2021-2022. 88 participants were selected by random sampling method and were divided into two groups including t2dm patients with metabolic syndrome in the experience group (n=55) compared with healthy subjects in the control group (n=38). triacylglycerol (tg), high-density lipoprotein-cholesterol (hdl-c), obesity (bmi), serum chemerin, hypertension (sbp), age, fasting blood glucose (fbg), and glycated haemoglobin (hba1c) were measured in the two studied groups. data were analyzed using t-test through spss 21 software.findings: a significant difference was observed between the levels of bmi, sbp, fbg, tg, hdl-c, chemerin weight, dbp, and hba1c in the studied groups (p=0.05). the rate of wc and hdl-c was higher in the females than in males in the experience group. while, there was a significant increase in the rates of sbp, fbg, tg, and chemerin in males than females. a positive correlation coefficient was observed between age, sbp, wc, bmi, fbg, tg, and hba1c with chemerin level in the experience group. conclusion: an increase in chemerin level is associated with a high level of triglycerides during the onset of symptoms of metabolic syndrome, age, and gender, which affect the increase of adipokine.
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کلیدواژه
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metabolic syndrome; angiogenesis; t2dm; aging process; adipokines
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آدرس
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university of basrah, al-zahraa college of medicine, department of biochemistry, iraq, university of misan, al- manara college for medical sciences, department of dentistry, iraq, university of misan, college of science, department of chemistry, iraq, middle technical university, college of health and medical techniquse, iraq
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Authors
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