studying the role of interleukin-6, c-reactive protein, and nitric oxide synthase in obese, diabetic, and sub-fertile men

Aims: this study aimed to investigate the role of interleukin-6, c-reactive protein, and nitric oxide synthase in obese, diabetic, and sub-fertile men. material & methods: the current study was conducted in some health centers in misan province, iraq, from december 2020 to july 2021. the whole sample included 80 men aged 35-45 years, divided into four groups (20 men/group). eight to ten milliliters of venous blood samples were drawn at 9 - 11 am, using a disposable needle and plastic syringes for each man. the blood was left at room temperature for 15 minutes for coagulation, centrifuged at 3000rpm for 5 minutes, then serum and plasma were separated and transferred for storage. statistical analysis was performed by ibm spss 23 using anova.findings: results revealed: interleukin-6 increased significantly (p<0.05), except in the diabetic group, in different groups in comparison with the control, c-reactive protein increased significantly (p<0.05) in different groups in comparison with the control, nitric oxide synthase decreased significantly (p<0.05), except in sub-fertility group, in different groups in comparison with the control. conclusion: the interleukin-6 and c-reactive protein increment and nitric oxide synthase reduction in different groups might be indicated a pro-inflammatory action and low fertility in obesity, diabetic and sub-fertility groups.