comparison of the antimicrobial activity of nigella sativa aqueous and oil extracts

Aims: nigella sativa is recognized as a black seed. it is a grassy plant relating to the ranunculaceae family. there are various reports regarding this plant’s pharmacological and biological action, like antihypertensive effects, antibacterial, anticancer, antioxidants, antifungal, pain alleviating, anti-inflammatory, antidiabetic, and immune-modulatory effects. this study aimed to compare the anti-microbial activity of aqueous and oil extract of nigella sativa against selected gram-positive and gram-negative bacteria.materials & methods: nigella sativa aqueous and oil extracts were gathered via a retail food shop (al-hilla) 2018. gram-positive (staphylococcus aureus; streptococcus pneumonia; streptococcus pyogenes) and gram-negative (salmonella typhi; escherichia coli; pseudomonas aeroginosa) isolates (obtained via clinical specimens) were utilized.findings: both nigella sativa aqueous and oil extracts showed a maximum inhibition zone against e. coli and minimum inhibition against s. pyogenes.conclusion: nigella sativa acts against gram-positive as well as gram-negative bacterial isolates.