Evaluation of the Bioactive Potential of Secondary Metabolites Produced by a New Marine Micrococcus Species Isolated from the Persian Gulf

Background: in the present work, a newly isolated marine bacterium, micrococcus sp. mp76, from coastal area of persian gulf around bushehr province, iran, was identified with the ability to produce bioactive compounds. methods: the pigment production was optimized by changing carbon and nitrogen sources in bacterial growth media at 28c and 220 rpm for 5 days. partial purification of the pigment was carried out using suitable solvents. results: maximum pigment extract was achieved (1.4 g/l) when cultured in the medium containing 0.5% (v/v) molasses, 0.5% (w/v) peptone, 1% (w/v) sea salt, 0.01% (w/v) potassium phosphate, and 0.05% (w/v) yeast extract, ph=7.0. antibacterial effect assessment of the extract against pathogenic bacteria revealed the mic values in the range of 4.2-7.5 mg/ml depending on different pathogens. the pigment extracted from medium supplemented by molasses and ammonium sulfate had 81% radical scavenging activity, and its ic50 value was 0.28 mg/ml. conclusion: the newly isolated strain of micrococcus genus from the persian gulf revealed a valuable source to access worth medicinal ingredients when cultured under optimized conditions.