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An Enhancing Effect of Gold Nanoparticles on the Lethal Action of 2450 MHz Electromagnetic Radiation in Microwave Oven
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نویسنده
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Mollazadeh-Moghaddam Kamyar ,Varasteh Moradi Bardia ,Dolatabadi-Bazaz Reza ,Shakibae Mojtaba ,Shahverdi Ahmad Reza
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منبع
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avicenna journal of medical biotechnology - 2011 - دوره : 3 - شماره : 4 - صفحه:195 -200
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چکیده
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Today, there is an increasing interest in the use of metal nanoparticles in health sciences. amongst all nanoparticles, the gold nanoparticles have been known to kill the cancer cells under hyperthermic condition by near-infrared frequency electromagnetic waves. on the other hand, although there are dif- ferent physiochemical methods for disinfection of microbial pollution, however applications of irradiated gold nanoparticles against microorganisms have not yet been investigated. in this study, gold nanoparticles were prepared using d-glucose and characterized (particle size <26 nm). in the next step, the en- hancing effect of the non toxic level of gold nanoparticles (50 μg/ml) on the antimicrobial activity of 2450 mhz electromagnetic radiation generated at a microwave oven operated at low power (100 w), was investigated by time- kill course assay against staphylococcus aureus (s.aureus) atcc 29737. the results showed that application of gold nanoparticles can enhance the lethal effect of low power microwave in a very short exposure time (5 s).
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کلیدواژه
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Antimicrobial effect ,Electromagnetic radiation ,Gold nanoparticles ,Microwave ,Staphylococcus aureus
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آدرس
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tehran university of medical sciences tums, Students' Scientific Research Center, ایران, tehran university of medical sciences tums, Faculty of Pharmacy, Department of Pharmaceutical Biotechnology and Biotechnology Research Center, ایران, tehran university of medical sciences tums, Faculty of Pharmacy, Department of Medicinal Chemistry, ایران, kerman university of medical sciences, School of Pharmacy, Pharmaceutics Research Center, Department of Pharmacognosy and Biotechnology, ایران, tehran university of medical sciences tums, Faculty of Pharmacy, Department of Pharmaceutical Biotechnology and Biotechnology Research Center, ایران
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پست الکترونیکی
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shahverd@sina.tums.ac.ir
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Authors
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