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Antinociceptive and Antipyretic Activities of Amaranthus Viridis Linn in Different Experimental Models
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نویسنده
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Ashok Kumar Bagepalli Srinivas ,Lakshman Kuruba ,Narsimha Jayaveera Korala Konta ,Shekar Devangam Sheshadri ,Muragan Chinna SwamyVel ,Manoj Bachappa
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منبع
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avicenna journal of medical biotechnology - 2009 - دوره : 1 - شماره : 3 - صفحه:167 -171
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چکیده
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Methanolic extract of whole plant of amaranthus viridis l (meav), was screened for antinociceptive activity using acetic acid induced writhing test, hot plate test and tail immersion test in mice. in a similar way a screening exercise was carried out to determine the antipyretic potential of the extract using yeast induced pyrexia method in rats. administration of the extracts was applied to both laboratory animals at the doses of 200 and 400 mg/kg body weight, respectively. the results of the statistical analysis showed that meav had significant (p<0.01) dose dependent antinociceptive and antipyretic properties at 200 and 400 mg/kg. hence present investigation reveals the antinociceptive and antipyretic activities of methanolic extract of amaranthus viridis.
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کلیدواژه
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Analgesics ,Animals ,Dose response relationship ,Methanol ,Plant extracts
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آدرس
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Sri K.V.College of Pharmacy, Department of Pharmacognosy, India, PES College of Pharmacy, Department of Pharmacognosy, India, Jawaharlal Nehru Technological University, College of Engineering, Department of Chemistry, India, Sri K.V.College of Pharmacy, Department of Pharmacology, India, Sri K.V.College of Pharmacy, Department of Pharmacology, India, Sri K.V.College of Pharmacy, Department of Pharmacognosy, India
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پست الکترونیکی
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ashok4vani@gmail.com
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Authors
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