Association between ELF and RF electromagnetic field and Leukemia

Extremely low frequency (elf) electromagnetic field (elf-emfs) are extensively employed in electrical appliances and different equipment such as tv sets, elf-emfs can affect biological systems by intensifying generation ros. the changed balance between ros generation and elimination plays a important role in a diversity of pathologic conditions. ros levels have been observed in some hematopoietic malignancies including acute and chronic myeloid leukemia. elf-emfs exposure significantly reduced nitric oxide synthase (inos) protein expression lower levels of no have been proved to exert a protective role in leukemic and melanoma cells and to prevent effector caspases by s-nitrosylation. also elf-emfs can reduction melatonin production by effects on n-acetyltransferase. melatonin is an antioxidant, impressive in protecting dna. transmitters emitting radio frequency electromagnetic fields (rf-emfs) are generally not located in residential areas but some epidemiology studies showed correlation distance transmitters from residential area and leukemia.