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The structure Biology and Application of Phytohemagglutinin (PHA) in Phytomedicine: With special up-to-date references to lectins
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نویسنده
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Movafagh Abolfazl ,Ghanati Kiandokht ,Amani Davar ,Mahdavi Seyed Mohammad ,Hashemi Mehrdad ,Zare Abdolahi Davood ,Darvish Hossein ,Gholami Milad ,HaghNejad Leyla ,Mosammami Sara ,Safari Shamsi ,Darehgazani Reyhaneh ,Rahimi Mahnoosh ,Zamani Mahdi ,Ghandehari Motlagh Mehdi ,Safavi Naini Nilofar
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منبع
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archives of advances in biosciences - 2013 - دوره : 4 - شماره : supplement - صفحه:126 -141
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چکیده
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Lectins first discovered more than 100 years ago in plants, they are now known to be present throughout nature. phytohemagglutinin (pha), the lectin extract from the red kidney bean (phaseolus vulgaris), contain potent, cell agglutinating and mitogenic activities. they play a role in biological recognition phenomena involving cells and proteins towards medical applications. the present article is a brief review of the history of lectin in nature. by reviewing the web-based search for all types of peer review articles published, was initiated using isi web of sciences and medline / pubmed, and other pertinent references on websites about lectins. here, we present a brief account of 100-plus years of lectin research and show how these proteins have become the focus of intense interest for biologists and in particular for the research and applications in medicine. phytohemagglutinin, has been widely used for mitotic stimulation to human lymphocytes, cell arrest, or apoptosis, potential sources for developing novel pharmaceutical preparation and intensive interest for health care services, biologist and phytomedicine research can be considered.
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کلیدواژه
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Lectins ,PHA ,Significant role ,Cell ,Biology ,Medicine
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آدرس
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shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Research Departmant of The International Branch of Shahid Beheshti University of Medical Sciences & Health Services, ایران, shahid beheshti university of medical sciences, Department of Immunology, School of Medicine, ایران, shahid beheshti university of medical sciences, Faculty of Paramedical Sciences, Proteomics Research Center, ایران, islamic azad university, Department of Genetics, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران, tehran university of medical sciences tums, Department of Medical Genetics, School of Medicine, ایران, tehran university of medical sciences tums, School of Dentistry, Pediatric Dentistry, ایران, shahid beheshti university of medical sciences, Department of Medical Genetics, Faculty of Medicine, ایران
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Authors
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