risk of increased expression of ace2 membrane protein in patients with hypertension: review of covid-19

Context: in late 2019, covid-19 launched a pandemic from around wuhan, china. it`s called the sars-cov-2 virus which belongs to the corona family and it has a lot in common with sars-cov-2, but it has been reported to be more common. evidence acquisition: the risk of the virus is high for people with high blood pressure and use medication. the reason for this potential and risk for covid- 19 is an increase in expression in a membrane protein called ace2. this protein is responsible for converting ang i to ang1-9 as well as converting ang ii to ang1-7. results: its pathogenic role is due to its receptor for sars-cov-2 and sarscov. research has shown that there is a significant link between hypertension, increase the expression and activity of ace2 and having coronavirus. that`s why our goal is to remind people of high blood pressure about the risk of developing covid-19. we studied ace2 and covid-19 from a clinical and biological point of view. in the following we have shown the position and the type of virus connection to ace2 with the help of protein database. conclusion: in the sars-cov-2, there are four structural proteins and several non-structural proteins together with capsid can contain positive-stranded rna viruses. studies have shown that the spike (s) protein binds strongly to the chain e and f with the ace2 receptor.