Primary adrenal insufficiency (Addison’s disease) associated with systemic lupus erythematosus: A rare occurrence

Coexistence of addison’s disease and systemic lupus erythematosus (sle) is a rare occurrence with only few reported cases in the literature. we describe a 29-year-old woman who presented to us with clinical features of acute addisonian crisis and sle. laboratory investigations were confirmatory of addison’s disease in a background of sle. the patient made remarkable improvement on administration of steroids as replacement therapy for adrenal insufficiency and treatment of sle. clinicians need to have a high-index of suspicion of this possible coexistence in order to avoid the associated deleterious hemodynamic and metabolic consequences. © 2014,isfahan university of medical sciences(iums). all rights reserved.