Gastroesophageal Reflux Disease in Iran: SEPAHAN Systematic Review No. 2

Background: gastroesophageal reflux disease (gerd) is one ofthe most prevalent disorders affecting gastrointestinal tract with a widerange of frequency around the world. in this study, we aimed to reviewall of the published studies about gerd’s prevalence in iran systematically.methods: we searched bibliographic databases including pubmedand google scholar and local databases (scientific information databaseand iran medex) to achieve all relevant articles to our subject andincluded them based on predefined inclusion criteria.results: twenty-two articles were included in the study to estimatethe prevalence of gerd in iran. based on these articles, the prevalenceof gerd in iran was within the range of 1.9 to 52%.conclusions: due to the differences between studies, such ascharacteristics of the sampled population and the diagnostic criteria,the reported prevalence of gerd was remarkably different in thereviewed studies. nonetheless, because of the high prevalence ofgerd in iran, conducting large-scale epidemiological studies shouldbe considered to determine factors associated with the prevalence ofgerd to prevent and control it.